(Sports Network) - The Chicago White Sox try and avoid their sixth straight loss this evening when they open a four-game set with the Tampa Bay Devil Rays at Tropicana Field.

Chicago has dropped 22 of its last 27 games and was swept in a three-game set over the weekend by the Cubs at U.S. Cellular Field, culminating with a 3-0 shutout on Sunday.

White Sox starter Jose Contreras (5-8) allowed two runs on 10 hits, while walking none and fanning three over seven innings.

Tadahito Iguchi had three hits for Chicago, which is in the midst of its fourth five-game losing streak of the season. The Pale Hose have not lost six in a row, though, since a seven-game slide from August 12-20, 2005.

Hoping to get the Sox back on track tonight will be 22-year-old left-hander John Danks, who is 3-6 with a 4.61 earned run average and is winless in his last five starts. Danks received a no-decision in his last start on Tuesday against the Florida Marlins, as he allowed four runs and eight hits in four innings of his team's 7-5 loss.

Tampa will counter with lefty J.P. Howell, who is 1-1 with a 4.26 ERA. Howell also received a no-decision in his last appearance on Tuesday against Arizona, surrendering four runs and nine hits in 5 1/3 innings of a 10-8 loss.

Both starters will be facing their opponents for the first time in their young careers.

Tampa enters this series on a winning note after taking the final two games of its three-game set over the weekend from the Los Angeles Dodgers. On Sunday, Ty Wigginton went 2-for-3 with a solo home run, two runs batted in and a pair of runs scored to lead the D-Rays to a 9-4 win.

Carl Crawford chipped in with a two-run double and Delmon Young knocked in a pair for the Rays, whose winning streak comes on the heels of a three-game skid.

Edwin Jackson (1-8) pitched a solid six innings, allowing two runs on nine hits. The right-hander struck out a pair and walked a batter. It was the veteran's first major league win since September 26, 2005 when he was a member of the Dodgers and won a 9-4 decision against the Pittsburgh Pirates.

These teams split a rain-shortened two-game series earlier in the year and have split the last eight matchups. Chicago, though, is 12-8 in the series since the start of the 2004 campaign.